Bactrim

Bactrim general precautions and side effects

Bactrim (sulfamethoxazole and trimethoprim) tablets should be prescribed only in the presence of a justified or strongly believed bacterial infection. Besides, the medicine is not recommended to be used as a prophylactic measure as it may lead to the development of drug-resistant bacteria. This antibiotic should be used with great caution by people with affected kidney or liver function.

Those patients, who may have folate deficiency, should use this medicine under supervision of a doctor. The other categories of patients who should be especially careful with antibiotic Bactrim are geriatric patients, people who abuse alcohol, patients receiving anticonvulsant therapy, patients with malabsorption syndrome, and patients in malnutrition states.

Bactrim is not used in patients with severe allergies or bronchial asthma. Trimethoprim has been detected to affect phenylalanine metabolism. Still it may be used in phenylketonuric patients if they follow special diet.

Bactrim possible side events

Any antibiotic may cause side effects which can be minor to serious. Serious side events should be immediately managed. Less serious side effects usually disappear after the medicine is stopped.

These includes: • vomiting; • painful or swollen tongue; • dizziness, spinning sensation; • ringing in your ears; or • insomnia. Other medicines may affect Bactrim. Thus it is absolutely necessary to discuss with your doctor the possibility of drug interactions with Bactrim.

Bactrim dosage and application

Bactrim is used to manage UTI (urinary tract infections) and shigellosis in adult and pediatric patients. The medicine is also applied to treat acute otitis media in pediatric patients.bac
Adult dose for UTI:
1 Bactrim DS (double strength) tablet or 2 Bactrim tablets every 12 hours for 10 to 14 days.
Adult dose for Shigellosis:
1 Bactrim DS (double strength) tablet or 2 Bactrim tablets every 12 hours for 5 days.
Children dose for UTI/ acut otitis media:
40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim per 24 hours, given in two divided doses every 12 hours for 10 days.
Children dose for shigellosis:
40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim per 24 hours, given in two divided doses every 12 hours for 5 days.
Adult dose for chronic bronchitis:
1 Bactrim DS (double strength) tablet or 2 Bactrim tablets every 12 hours for 14 days.
Adult dose for traveler’s diarrhea:
1 Bactrim DS (double strength) tablet or 2 Bactrim tablets every 12 hours for 5 days.
Before treatment a doctor should be informed if a patients:
•    Has kidney or liver disease;
•    Has folic acid deficiency;
•    Has asthma or severe allergies;
•    Has a thyroid disorder;
•    Has HIV or AIDS;
•    Has a glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency);
•    Is  malnourished;
•    Is taking other medicines;
•    Is pregnant.
Bactrim should be taken as prescribed by your doctor. The medicine should be consumed regularly during the period of time prescribed.

Bactrim contraindications

The use of Bactrim is contraindicated in patients who have infections caused by viruses or who have symptoms of the common cold.
To diminish the growth of antibiotic-resistant microorganisms and keep the effectiveness of antibiotics including Bactrim, the antibiotic therapy should be initiated only with a doctor’s approval in cases when the disease is believed or clinically proven to be caused by susceptible bacteria.
Bactrim is not used in patients with a known (or suspected) hypersensitivity to trimethoprim or sulfonamides.
Patients with megaloblastic anemia caused by shortage of folate should not use Bactrim.
Bactrim use is contraindicated in pregnant women and nursing mothers. The main components of this medication can penetrate to the placenta and are found in the milk and may cause kernicterus.
Bactrim is contraindicated in children younger than 2 months of age.
The use of this medication is not prescribed for patients with diagnosed hepatic damage or severe renal insufficiency.

What is it?

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This drug contains a combination of trimethoprim and sulfamethoxazole  and is supplied in  a liquid suspension and tablets. Trimethoprim and sulfamethoxazole  are  antibiotics that treat different types of infection caused by bacteria.

This drug is used to treat  urinary tract infections, Pneumocystis jiroveci pneumonia, ear infections, traveler’s diarrhea, bronchitis,shigellosis.

Bactrim with other drugs

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Tell your specialist of health about all other drugs, which you use, especially:

  •     an antidepressant;
  •     a blood thinner: warfarin (Jantoven,Coumadin);
  •     cyclosporine (Neoral, Gengraf,Sandimmune);
  •     oral diabetes medication;
  •     digoxin (Lanoxicaps, Lanoxin);
  •     blood pressure /heart drugs: captopril (Capoten),benazepril (Lotensin), enalapril (Vasotec), fosinopril (Monopril),  lisinopril ( Zestril, Prinivil), perindopril (Aceon), moexipril (Univasc), quinapril (Accupril),  or trandolapril   (Mavik), ramipril (Altace);
  •     a diuretic (water pill);
  •     indomethacin (Indocin);
  •     calcium folinate, leucovorin;
  •     methotrexate (Rheumatrex, Trexall );
  •     seizure medication such as phenytoin (Dilantin);