Bactrim (sulfamethoxazole and trimethoprim) is a synthetic antibacterial sulfonamide combination from the pharmacological class of folic acid antagonists.bactrim australia
Bactrim contains two antibiotic agents: sulfamethoxazole and trimethoprim. The medication is supplied in tablets and a liquid suspension. The tablets of Bactrim for oral use contain either 800 mg of sulfamethoxazole and 160 mg of trimethoprim or 400 mg ofsulfamethoxazole and 80 mg trimethoprim.
The combination of antimicrobial agents in Bactrim allows using it for a variety of infections caused by bacteria. The medication is indicated to treat urinary tract infections, bronchitis, otitis media, shigellosis (bacillary dysentery), traveler’s diarrhea, and Pneumocystis jiroveci pneumonia. This antibiotic is used in patients with autoimmune diseases caused by different types of cancers, transplant recipients, AIDS patients whose immune system is weak and does not function properly.
The antibiotic mixture in Bactrim fights and eliminates the bacteria in the body. It can be also used to prevent pneumonia in some patients.
Bactim is available only with a doctor’s prescription.

Bactrim is quickly absorbed and distributed in the tissues after oral use. The two main components in the medication present in the blood as unbound, protein-bound and metabolites.
70% of sulfamethoxazole and 44% of trimethoprim are protein – bound.
The max plasma concentrations of these components are reached within 1- 4 hours post oral use. The mean terminal half-lives of sulfamethoxazole and trimethoprim are 10 and 8 to 10 hours, accordingly. In patients with kidney disease the half-lives of both components are significantly increased. Such patients should be administered lower doses of the medication or prescribed other antibiotics.
The elimination of the medication occurs mainly by the kidneys. Urine concentrations of both components are greater than their concentrations in the blood.
Bactrim is detected to be distributed to sputum, vaginal fluid and middle ear fluid; trimethoprim, bronchial secretion. The antibiotic components in the medication pass the placental barrier and are found in human milk.

Bactrim AuBactrim medication is available only with a doctor’s prescription. A patient should not use it without a doctor’s approval. Bactrim should be applied only when the infectious disease is strongly suspected or proven by tests to be caused by susceptible bacteria. This measure will help to diminish the chance of antibiotic-resistant bacteria development.
If a patient is prescribed this medication, he/she should follow all the doctor’s instructions on how to use and store it. It is not allowed to discontinue the treatment even if the symptoms of the condition disappear within the first days of the therapy. Skipping doses or missing them also increases the chance for further development of the infection.
Bactrim should not be used in patients with allergic reactions to any component in Bactrim.
This antibiotic medication is not used in pregnant or breast-feeding women.
Patients with anemia caused by folic acid deficiency or severe kidney impairment should not use Bactrim.
Before using any antibiotic it is necessary to visit a doctor for consultation and discuss with him/ her medical history of yours.
Bactrim is an antibiotic; it is not indicated to treat viral infections or common cold.